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Max Mello, PA-CCareer coaching for PAs, NPs and CRNAs

Nurse practitioner salary in Mississippi

Mississippi nurse practitioners earn a median of $124,730 a year ($59.96 an hour), according to BLS data for May 2025. That is 6% below the national median of $132,300, and ranks 47th of 51 states.

Median, Mississippi

$124,730

Mean $125,340

Middle half earns

$106,660 to $134,020

US: $117,990 to $156,700

Employed in Mississippi

4,690

1.94x the national concentration

Where Mississippi sits in the range

Mississippi

Statewide

United States

National

Memphis

Metro area

Jackson

Metro area

Gulfport

Metro area

Hattiesburg

Metro area

Line: 10th to 90th percentile. Bar: 25th to 75th. Tick: median. Annual wages, BLS OEWS, May 2025.

Nurse practitioner pay by percentile

Ten percent of Mississippi nurse practitioners earned less than $98,780 and ten percent earned more than $156,830, a spread of $58,050. Where you land depends mostly on specialty, setting, experience and how the productivity pay is built, which is why two offers in the same city can be far apart.

Annual wages, BLS OEWS, May 2025
PercentileMississippiUnited StatesDifference
10th$98,780$101,340-2.5%
25th$106,660$117,990-9.6%
Median$124,730$132,300-5.7%
75th$134,020$156,700-14.5%
90th$156,830$174,420-10.1%

Nurse practitioner pay by metro area

BLS published NP pay for 4 metro areas that include part of Mississippi. Gulfport-Biloxi, MS has the highest median at $128,150. Metro estimates rest on smaller samples than the statewide figure, so treat a low-precision row as a direction, not a number.

Annual wages, BLS OEWS, May 2025
Metro areaEmployedMedianMiddle half
Memphis, TN-MS-AR1,800$124,600$106,670 to $134,300
Jackson, MS1,310$124,730$109,360 to $134,020
Gulfport-Biloxi, MS600$128,150$110,670 to $140,700
Hattiesburg, MSmoderate precision340$113,300$104,990 to $128,290

How NP pay compares with other clinicians in Mississippi

Median annual wage, BLS OEWS, May 2025
OccupationMississippiUnited States
Nurse practitioner$124,730$132,300
Physician assistant$105,920$135,880
Nurse anesthetist (CRNA)$198,410$236,590
Registered nurse$77,090$97,550

The Mississippi NP workforce

BLS counts 4,690 nurse practitioners on Mississippi payrolls, or 4.04 for every 1,000 jobs in the state, more concentrated than in the country as a whole. The federal NPI registry, which also counts self-employed and part-time clinicians, lists 6,069 nurse practitioners with a Mississippi practice address, and 311 new NP NPIs there in the past twelve months.

Using these numbers when you negotiate

A state median is a reference point, not a target. If an offer comes in under $106,660, it sits in the bottom quarter of what Mississippi nurse practitioners earn, and you should know why before you sign: a new-grad rate, a light schedule, or a base kept low because a productivity bonus is supposed to make up the difference. If it is above $134,020, ask what is expected in return, such as call, volume targets or a longer non-compete.

Compare the whole package, not the base: how the bonus is calculated, call pay, CME, PTO and who pays malpractice tail coverage. The negotiation guide and the contract checklist walk through each term.

Questions about NP pay in Mississippi

How much does a NP make in Mississippi?

The median annual wage for nurse practitioners in Mississippi was $124,730 in May 2025, and the mean was $125,340, per the BLS. The middle half earned between $106,660 and $134,020.

What is the hourly rate for nurse practitioners in Mississippi?

The median hourly wage was $59.96 and the mean was $60.26. BLS computes hourly figures from annual pay assuming a full-time year, so per-shift or per-diem rates can differ.

Where do NPs earn the most in Mississippi?

Among Mississippi metro areas with published data, Gulfport-Biloxi, MS had the highest median at $128,150, and Hattiesburg, MS the lowest at $113,300.

How does Mississippi rank for NP pay?

Mississippi ranks 47th of 51 states (including DC) by median NP pay, 6% below the national median of $132,300. Pay is only half the picture: compare it with what housing and taxes cost where you would live.

How many nurse practitioners work in Mississippi?

BLS estimated 4,690 nurse practitioners employed in Mississippi in May 2025. The federal NPI registry lists 6,069 with a Mississippi practice address.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 (bls.gov/oes), SOC 29-1171, all industries and ownerships. NPI counts: NPPES monthly file, August 2026 (CMS, public domain). BLS wages are straight-time pay: they include production bonuses but leave out overtime, shift differentials, non-production bonuses and benefits, and they exclude the self-employed.

Have an offer on the table?

Book a free intro call with Max. Tell him what you are weighing, and he will tell you whether coaching would help, or whether you just need a few answers.